Neuro Care 2026

Title: Eliminating implant failure in humans: 30,000 cases and counting

Nanomedicine is the use of nanomaterials to improve disease prevention, detection, and treatment which has resulted in hundreds of FDA approved medical products. While nanomedicine has been around for several decades, new technological advances are pushing its boundaries. For exa [....] » Read More

Title: Traumatic brain injury, whats new?

Definition and Types: TBI is an injury to the brain caused by external force, resulting in a range of effects. It can be classified as mild (concussions), moderate, or severe based on symptoms and impact. Causes: Common causes include falls, vehicle accidents, sports in [....] » Read More

Title: Neurobiology of Addiction

Addiction was historically viewed as a disease of “weak personality” and was not systematically addressed by the scientific and medical communities until the latter half of the 20th century.  They are now commonly accepted as diseases of the brain caused by the i [....] » Read More

Title: Neurological effects of spinal manipulation: What do we know?

Introduction: Spinal manipulation (SM) is a key therapeutic procedure of chiropractic healthcare and a component of osteopathy, physical therapy, Traditional Chinese Medicine and other healthcare professions. It is most commonly used to address musculoskeletal pain and [ublished [....] » Read More

Title: Spatial transcriptomics and snRNA-seq unravel cell-cell interactions and signaling pathways in the entorhinal cortex driving Alzheimer’s disease initiation and progression

Background: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by complex molecular and cellular changes that lead to cognitive decline and dementia. The entorhinal cortex (EC) is one of the earliest cortical regions affected in AD, and the p [....] » Read More

Title: Study of resilience in cases of incest, father-daughter, step-father and step-daughter in the pre-pubber and puberous period among adult women and mothers: How to overcome the traumatisms of an incestuous relationship?

Sexual abuse of a child is a form of maltreatment. Among recent studies in this area, the Canadian study (Burczycka and Conroy, 2017) indicates that 70.3% are intrafamilial abuse and that of all cases of sexual abuse, 81% of victims are female (Silva and Collin-Vézina, 2 [....] » Read More

Title: Neurological and cardiac complications of covid-19 among Chinese and south Asians in Ontario-waves 1,2 and 3: a population-based Canadian study

Background: Although we had previously reported the cardiac and neurologic outcomes of Chinese and South Asian Ontarians in wave 1 of COVID-19, data on subsequent waves of COVID-19 remain unexamined.This is an extension study of this cohort in waves 2 and 3.   Methods: [....] » Read More

Title: Neurological complications of immune check point inhibitor therapy: A report of two cases from Canada

INTRODUCTION: Presentation of 2 challenging cases of severe neurological complications of cancer immunotherapy.   LEARNING NEUROLOGY: ONE CASE AT A TIME Review the pathogenesis of immune-related adverse events (irAEs) of immune checkpoint inhibitors (ICI) cancer [....] » Read More

Title: Physical exercise activates a PVN-NAc oxytocin circuit to relieve stressinduced depressive-like behaviors

Physical exercise is known to reduce depression, but the underlying brain mechanisms SAMPLE ABSTRACT TEMPLATE  remain unclear. Based on a chronic restraint stress model in mice, we showed that 4-week treadmill exercise profoundly maintained normal neural activity in the nucl [....] » Read More

Title: Bio-RECURSION or DNA-comp and Brain-BLOCKCHAIN as nerves nets by GENES

In the last decade, a radically different scientific concept of developing Life on Earth as Bio-RECURSION, or Neuro-BLOCKCHAIN - has emerged. From the point of view of this concept, Life is Evolutional formation of Closed-Loop Coding-Decoding (CL-CD) chem-matter (bio-chem) proced [....] » Read More

Title: Traumatic Millard-Gubler syndrome: Case report

Introduction: Millard-Gubler syndrome is caused by a lesion in the ventral and caudal area of the pons, with a clinical manifestation of an alternating brainstem syndrome, characterized by paralysis of the sixth and seventh cranial nerves on the side of the lesion and contralater [....] » Read More

Title: Poland syndrome combined with facial palsy: A case report

Poland Syndrome is a congenital malformation marked by incomplete development or absence of the pectoralis major muscle on unilateral side of the chest, typically associated with abnormalities in the ipsilateral upper limb (1). The most accepted explanation is that, around the si [....] » Read More

Title: Analysing human behaviour and health by means of a large-area capacitive sensor floor

People are in almost constant contact with the floor throughout the day. With high-resolution sensors discreetly installed under the floor covering, data on the number, location, direction of movement, and speed of individuals can be recorded continuously. In addition to detectin [....] » Read More

Title: Psychological challenges in burn patients

With the increased survival of patients with large burns comes a new focus on the psychological challenges and recovery that such patients must face. Most burn centres employ social workers, vocational counsellors, and psychologists as part of the multidisciplinary burn team. Phy [....] » Read More

Title: Ethylmethylhydroxypyridine succinate (Mexidol®): Mechanisms and clinical evidence in ischemic stroke

Ethylmethylhydroxypyridine succinate (Mexidol®) is a medication whose efficacy is due to the combination of antioxidant, antihypoxic, and membrane-stabilizing effects. Ethylmethylhydroxypyridine succinate displays antioxidant activity by binding superoxide anion radicals, inc [....] » Read More

Title: Neurotropic and biophysics effects of Kyokushin Karate kata

Introduction. In Eastern martial arts, non-contact mental influence on a partner is described, often associated with the concept of "energy-informational exchange." The Kyokushin Karate Kata (KKK) practice is particularly noteworthy in this context. Objective. To exp [....] » Read More

Title: Migraine and oxidative stress

Migraine is a chronic neurovascular disorder characterized by acute, debilitating attacks, posing a significant public health challenge. The severity and duration of pain, along with the limited effectiveness of treatments for some patients, underscore the ongoing need for resear [....] » Read More

Title: A filipino child presenting with primrose syndrome with a deletion on the zbtb20 gene variant

Background: Intellectual disability in association with congenital anomalies affects 1-3% of the population, and due to its diversity, diagnosis can be challenging. Primrose syndrome is one of these rare genetic conditions that present with such disability and anomalies.  It [....] » Read More

Title: Innovations in sutureless nerve repair: combining bioadhesives and electrical stimulation for enhanced outcomes

Peripheral nerve injuries (PNIs) remain a significant neurological hurdle, with clinical manifestations varying based on the degree of axonal disruption. While progress has been made in understanding the underlying mechanisms of nerve damage and regeneration, achieving full funct [....] » Read More

Title: Enhancing post-stroke gait: effects of a 12-week core exercise intervention in hemiparetic survivors

Walking impairment is a major limitation following hemiparetic stroke, reducing functional independence and quality of life. Core-focused exercise has shown potential to enhance trunk stability and gait, yet evidence across different levels of motor impairment remains limited. Th [....] » Read More

Title: A way to use computers to figure out how chemical pathways affect brain function on a large scale

The study introduces a computational method for brain simulations using mean-field models with biophysical foundations, focusing on membrane conductances and synaptic receptors. It demonstrates that anesthetics targeting GABAA and NMDA receptors can cause brain changes to general [....] » Read More

Title: An approach of automating hippocampal volumetric tool for brain

Alzevita is a cloud-based AI tool developed to assist neuroradiologists and imaging professionals in brain MRI analysis through automated hippocampal segmentation and volumetric reporting. It provides improved consistency, speed, and clinical confidence in quantitative neuroimagi [....] » Read More

Title: A highly stable monomeric red fluorescent protein for advanced microscopy

The stability of fluorescent proteins (FPs) is crucial for many imaging techniques, including long-term. live cell imaging, super-resolution microscopy, correlative light and electron microscopy (CLEM), and tissue clearing. Although several stable green and yellow FPs are availab [....] » Read More

Title: The disease of sympathetic overdrive--A forgotten neurological disease?

The sympathetic nervous system participates in the functional regulation of numerous tissues and organs; its long-term excessive activation is closely associated with many related disorders. However, to date, the understanding of this symptom has been fragmented. The disease of s [....] » Read More

Title: APOE e4 homozygosity exacerbates retinal and cerebral microvascular dysfunction in alzheimer’s disease: A mediation analysis of vascular contributions to cognitive decline

BACKGROUND: APOE ε4 is the strongest genetic risk factor for Alzheimer’s disease (AD), with homozygous carriers (ε4/ε4) experiencing accelerated cognitive decline. While its role in amyloid and tau pathology is established, its impact on retinal and [....] » Read More

Title: Tai Chi-Induced Exosomal LRP1 is Associated with Memory Function and Hippocampal Plasticity in aMCI Patients

Background: Exercise, including Tai Chi (TC) was beneficial for cognitive function of older adults with aMCI. However, the underlying molecular mechanism of TC on neuroprotection remains largely unknown. Exercise-released exosomes have been identified as novel mediators of cel [....] » Read More

Title: Neurodevelopmental disorders in Saudi Arabia: A new era of precision diagnosis and personalized management

Neurodevelopmental disorders (NDDs) represent a significant public health challenge worldwide, and Saudi Arabia is no exception. With a unique population structure characterized by high rates of consanguinity, the Saudi population presents a distinct genetic landscape for NDDs. I [....] » Read More

Title: The effect of computerized cognitive rehabilitation on working memory, cognitive flexibility, and inhibitory control as executive functions in managers of an industrial organization

The purpose of the current research was to investigate the effectiveness of the cognitive training course based on the key cognitive factors for improving manager's performance. 30 managers in an organization in Tehran selected and randomly assigned to either the cognitive tr [....] » Read More

Title: Autophagic molecular alterations in the mouse cerebellum experimental autoimmune encephalomyelitis model following treatment with cannabidiol and fluoxetine

The crosstalk between autophagy and apoptosis is one of the most important processes involved in the cell program death, and several mechanisms including oligodendrocyte apoptosis and autophagy play significant roles in activating macrophages, microglial cells, and finally demyel [....] » Read More

Title: Pediatric neurodegenerative disorders and anesthesia considerations

Pediatric neurodegenerative disorders encompass a wide range of conditions that result from progressive damage to cells and nervous system connections that are essential for mobility, coordination, strength, sensation, and cognition. Neurodegenerative diseases affect millions of [....] » Read More

Title: Virtual and augmented reality in neurosurgery (First experiences in education and clinical practice)

Virtual Reality (VR) and Augmented Reality (AR) are innovative technologies that enhance the way surgical techniques are taught. In simulating surgical procedures, we integrate the immersiveness of Virtual Reality (IVR) with the method of cognitive-motor dual tasking (CMDT), simi [....] » Read More

Title: Foville syndrome with internuclear ophthalmoplegia in a filipino male with pontine ischemic stroke: A case report

INTRODUCTION Stroke is defined as a syndrome of acute, focal neurological deficit attributed to a vascular injury to a part of the brain which can either be due to infarction or hemorrhage. Brainstem stroke is considered the most lethal form of all strokes accounting for a sig [....] » Read More

Title: Artificial Intelligence-Driven DWI and FLAIR for the detection of early stroke changes: A systematic review

Background Timely detection of acute ischemic stroke is crucial for ensuring an appropriate standard of care and guiding reperfusion therapies. While MRI remains highly sensitive for identifying early ischemic changes, its interpretation is subject to inter-observer variabilit [....] » Read More

Title: Facial motor evoked potential with paired transcranial magnetic stimulation for hemifacial spasm

Objective: Microvascular decompression (MVD) is widely considered the treatment of choice for hemifacial spasm (HFS), but not all patients immediately benefit from it. Numerous electrophysiological tests have been employed to monitor the integrity of the facial nerve prior to, du [....] » Read More

Title: Differential effects of personal and historical events in AI life history-based reminiscence therapy for older adults with neurodegenerative diseases

Background: Reminiscence therapy is a widely used non-pharmacological approach for improving emotional well-being in older adults, particularly those with neurodegenerative diseases. While both autobiographical and collective memories can be therapeutic, little is known about [....] » Read More

Title: White matter hyperintensities, plasma biomarkers, and cognitive decline in Alzheimer’s disease: Insights from early- and late-onset subgroups and APOE e4 carriers

White matter hyperintensities (WMHs) are a prominent neuroimaging feature in Alzheimer’s disease (AD), but their relationship with plasma biomarkers, cognitive decline, and genetic factors like APOE ε4 remains poorly understood. This study investigates WMH volumes, [....] » Read More

Title: PET/CT reveals characteristic prefrontal- Posterior cingulate hypometabolism in anti- AMPAR encephalitis

We aimed to characterize the clinical presentation and cerebral metabolic patterns of Chinese adults with anti- AMPAR encephalitis using 18F- FDG PET/CT. Methods: From August 2016 to August 2022, we retrospectively identified patients from two neurology centers who were positive [....] » Read More

Title: Targeting a Modifiable GABAergic Deficit in the Left DLPFC for Preemptive Intervention in At-Risk Individuals with High Trait Anxiety

Trait anxiety, characterized by a stable predisposition to perceive environmental stimuli as threatening, represents a significant vulnerability factor for anxiety disorders in non-clinical populations. Neurobiological models posit that impaired inhibitory control within the d [....] » Read More

Title: In Silico and In Vitro methods in the characterization of Beta-Carotene as pharmaceutical material for the management of cholinergic neurotoxicity-associated neurovascular disorders

Molecular docking is widely used in the assessment of the therapeutic potential of pharmaceutical agents. The binding properties of beta-carotene (BC) to acetylcholine esterase (AChE) proteins were characterized using the molecular docking method. The mechanism of AChE inhibition [....] » Read More

Title: Parkinsonism- hyperpyrexia syndrome (PHS) following deep brain stimulator battery depletion – Case reports and review of literature

Parkinsonism- hyperpyrexia syndrome (PHS) could turn out to be a fatal neurological emergency that mimics neuroleptic malignant syndrome (NMS). It presents as acute systemic inflammatory response syndrome, worsening of rigidity, fever, autonomic symptoms, confusion with high LDH [....] » Read More

Title: New-Onset Generalized Seizure as the Initial Manifestation of Neuropsychiatric SLE (NPSLE)

Background: Neuropsychiatric SLE presents with a wide range of neurological features. Seizures occur in up to 20% of SLE patients but rarely serve as the initial presentation. Early differentiation from infectious meningo-encephalitis is essential, as timely immunosuppressive the [....] » Read More

Title: AI-based seizure detection in the pediatric population: A prisma 2020–guided systematic review

Background: Epilepsy affects over ten million children worldwide. In pediatrics, seizures are often difficult to identify, especially in neonates. Artificial intelligence (AI) provides automated solutions for seizure detection by analyzing EEG and multimodal data.   Ob [....] » Read More