Trisomy21/Down’s syndrome : From main chromosome 21 genes to potential future therapies

Trisomy 21 affects around 5 000 000 persons worldwide. The persons born with trisomy 21 have very different phenotypes according to their parental genes, to the way they are breeding and educated. The life expectancy of these persons is around 65 years in developped countries but lower in many other countries. Having a baby with trisomy 21 is still very frightening and conduct in many countries to abortion. But if scientist could find innovative therapies for very early fetus or child development, the choice may be different. A few chromosome 21 genes have been investigated in that direction. The present talk will give insight especially on 2 of them for approaching early developpment and two for early neurodegenerative aspects.

To be updated shortly..