Title : The disease of sympathetic overdrive--A forgotten neurological disease?

The sympathetic nervous system participates in the functional regulation of numerous tissues and organs; its long-term excessive activation is closely associated with many related disorders. However, to date, the understanding of this symptom has been fragmented. The disease of sympathetic overdrive (DSO) hypothesis systematically elaborates on the related problems. DSO encompasses a wide range, featuring the coexistence of multiple systems, somatic and psychological diseases, with lifestyle diseases as the predominant type; the associated risk factors are numerous, characterized by superposition, complexity, and a focus on lifestyle. A systematic comprehension of DSO can remedy the odd situation of the lack of disease diagnosis in the sympathetic nervous system, more profoundly identify the common pathological basis of many common diseases, and propose new strategic directions for the coordinated prevention and control of related issues.

Dr. Kong Jian is a Chinese physician specializing in cardiology, metabolic syndrome, geriatrics, and DSO. He received his Bachelor’s degree in Medicine in 1983 and Master’s degree in 1990 from the Medical University of Bethune, and later obtained his PhD in Medicine from Jilin University in 2004.

He worked as a Resident Doctor in Cardiology at the First Hospital of the Medical University of Jilin from 1983 to 1987. Since 1990, he has been serving at the Geriatric Center of the First Hospital of Jilin University, progressing through roles including Visiting Doctor, Vice Professor, Professor, and Professor-in-Chief.

He was also a visiting researcher at the University of British Columbia, Canada (1995–1996). His research interests include cardiology, metabolic syndrome, and geriatric medicine.