Chronic migraine is a debilitating neurological condition characterized by headache occurring on fifteen or more days per month, often accompanied by nausea, sensitivity to light and sound, and cognitive disturbances. Unlike episodic migraines, chronic migraine represents a complex pain syndrome involving abnormal brain excitability and altered pain processing.

The Chronic Migraine session investigates the neurobiological, genetic, and hormonal mechanisms that sustain chronic headache disorders. Researchers are examining cortical spreading depression, trigeminal nerve sensitization, and neurotransmitter dysregulation as key contributors.

At the Migraine Research Conference, experts discuss advanced diagnostic imaging, preventive medications, and neuromodulation therapies offering relief to patients unresponsive to conventional treatment. Topics include CGRP monoclonal antibodies, Botox injections, and non-invasive vagus-nerve stimulation.

Clinicians, neurologists, and pain specialists will learn how to optimize individualized care through behavioral therapy, lifestyle modification, and comorbidity management. The session also highlights gender-related influences, as migraines disproportionately affect women due to hormonal fluctuations.

Groundbreaking studies in Pain Medicine continue to uncover links between neural circuits, inflammation, and chronic pain persistence, guiding new preventive and therapeutic strategies.