Title : Study of the efficacy of PSIO glasses for the inhibition of melatonin

Several studies have showed the influence of the inhibition of melatonin by blue light (470 nm) (1) In the following report we have tested the effect of continuous blue light - emitted by a PSIO device without sound stimulations (the PSIO is a pair of glasses equipped with eye-glasses emitting colored lights and with an integrated MP3 player) - on the production of melatonin at 10 PM and the difference with an audio-visual stimulation (emitted with a PSIO device) using same wavelength range of blue light (470 nm). The study has considered four groups of students aged from 18 to 26 y.o. and the experiment was conducted at 10 PM when the curve of melatonin production has already begun to increase for one hour approximately. The four groups were proposed to rest on a comfortable clinic table with or without PSIO glasses, rest time being for all groups of 30 min; Group 1 was a control group doing just a rest without PSIO glasses in a room with controlled light at about 75 watts; Group 2 was designed as placebo group with a pair of PSIO glasses but emitting only a continuous

(670 nm) red light (without any sound stimulations). Group 2 was considered as a “placebo” group, as red light being known by several studies to have no effect on the inhibition of melatonin; Group 3 was the group practicing a similar session with same PSiO glasses but emitting only blue light (470 nm) on the continuous mode (without any sound stimulations) and Group 4 was a group practicing a normal session of audio-visual stimulation with a range of colored blue light (wavelength around 470 nm). Results have already showed that the control group (1) had a normal increase of melatonin production; the Placebo group (2) had a normal increase of melatonin production and was responding similarly to the control group thus proving that PSIO glasses has no placebo effect concerning the inhibition of melatonin. Group 3, the PSIO continuous blue light (470 nm) stimulation group was responding with a strong inhibition of melatonin, and a small decrease in melatonin level was actually recorded. Group 4, the PSIO audio-visual stimulation group obtained also a strong similar inhibition of melatonin. Preliminary conclusions are that PSIO glasses, using a continuous blue light stimulation (470 nm) or a range of pulsated emitting blue light stimulations combined with audio stimulations both have a strong inhibition effect on the melatonin production at 10 PM.

Keywords: melatonin inhibition; blue colored light; audio-visual stimulation; AVS; PSIO glasses device; IQ; 

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